
January 26, 2021
7 AM PST | 10 AM EST | 4 PM CET
Animal-Free Drug Safety Testing:
Challenges and Opportunities
Drug safety testing is an essential part of drug R&D. New drug candidates must be tested in animals before they can enter first-in-human trials. The current animal testing paradigm has proven advantages as well as significant weaknesses. Alternative methods are increasingly being used to compensate for these weaknesses. In this roundtable, our panelists will discuss challenges and opportunities for applying in vitro and in silico models in drug development to improve translation to patients. They will address key questions, such as:
- Do animals predict human drug safety correctly? What are the general limitations?
- How can we increase predictivity of drug safety for patients?
- What are the challenges for evaluating new therapeutic modalities?
- What are the most promising new animal-free technologies and testing strategies for risk assessment?
- What will drug safety risk assessment look like in 2030?