2019 Conference Agenda

Thursday, April 25, 2019

Podium Presentations

This year, we are bringing together an impressive line-up of speakers who will share their visions for how we can bring the bench closer to the bedside with emerging 3D cell technologies and examples of how they are applying 3D cell technologies in their work today. Poster presentations, representing a broad range of body-and organ-on-a-chip approaches, 3D cell technologies, and 3D tissue and disease models will be available for viewing throughout the day.  If you would like to share your innovative 3D cell-based research with the group, please submit a presentation abstract when you register for the conference.  Abstract submissions will close on April 22, 2019.  Download the program.

Registration & Poster Setup

  • 7:30 – 8:20 AM

Light breakfast and coffee

7:30 – 8:20 AM
8:20 – 8:30 AM

Welcome and Opening Remarks

  • 8:20 – 8:30 AM

Patrick Guye, PhD
Cephalion Technologies and Program Committee Chair

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8:30 – 9:15 AM
9:15 – 10 AM

3D Cell Technology in a New Era of Drug Discovery and Safety Testing

  • 9:15 – 10 AM

Armin Wolf, Prof., PhD
Technical University of Kaiserslautern and InSphero

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10 - 10:30 AM
10:30 - 11 AM

Assessing Human Immunocompetence with Preclinical 3D Models

  • 11 -11:30 AM

Matthew Wagoner, PhD
Takeda Pharmaceuticals

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11 -11:30 AM
11:30 - Noon
Noon - 1 PM
1 - 1:45 PM

Alternatives to Anlmal Testing: From Microphysiological to Micropathophysiological Models

  • 1 - 1:45 PM

Lena Smirnova, PhD
Johns Hopkins University Center for Alternatives to Animal Testing

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From Synthetic 3D Hydrogels to Genetically Engineered Self-Assembled 3D Tissues

  • 1:45 - 2:15 PM

Parastoo Khoshakhlagh, PhD
GC Therapeutics

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1:45 - 2:15 PM
2:15 - 2:45 PM

Multicellular Tumor-on-a-Chip Model for Studies of Early Metastasis.

  • 2:15 - 2:45 PM

Huu Tuan Nguyen, PhD
MIT Biological Engineering Department

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2:45 - 3:15 PM
3:15 - 3:45 PM

Extracting Rich Information from Microscopy Images for Drug Discovery

  • 3:15 - 3:45 PM

Anne Carpenter, PhD
The Broad Institute of Harvard and MIT

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Group Discussion

  • 3:45 - 4:30 PM

Chaired by Patrick Guye, PhD
Cephalion Technologies and Program Committee Chair

3:45 - 4:30 PM
4:30 - 5:30 PM

Networking Reception and Poster Session

  • 4:30 - 5:30 PM

Wine, beer, and light hors d'oeuvres

Poster Presentations

Body and Organ-on-a-Chip


B-1 – Fat-on-a-chip model of human subcutaneous adipose tissue
Trivia Frazier, President & CEO, Obatala Sciences Inc.


B-2 – A micro-physiological system designed for ease of adoption
Caleb Horst, President, CellScale Biomaterials Testing


B-3 – Multicellular tumor-on-a-chip model for studies of early metastasis
Huu Tuan Nguyen, Postdoctoral Associate, MIT


B-4 – Applications of organ-on-a-chip systems in DMPK
Olivier Frey, Head of Technology Platforms, InSphero

3D Cell Technologies


C-1 – TISSUESPEC® extracellular matrix substrates for 3D cell culture
John O’Neill, Chief Scientific Officer, Xylyx Bio, Inc.


C-2 – The Organovir network: building 3D cell models for virology
Katja Wolthers, Clinical Virologist, Amsterdam UMC


C-3 – A novel low-volume, highly specific ELISA for the measurement of glucagon in human or rodent 
José M. Cacicedo, Research & Development Scientist, ALPCO


C-4 – A highly specific chemiluminescent assay to accurately measure low fasted levels of active GLP-1 (7-36) amide
José M. Cacicedo, Research & Development Scientist, ALPCO


C-5 – TempO-Seq transcriptome analysis of 3D liver microtissues and its use in detecting toxicological key events
Harper Van Steenhouse, Director, Tech Integration, BioSpyder


C-6 – Real-time apoptosis and necrosis detection in 3D spheroid cell models
Kyle Hooper, Channel Marketing Manager, Promega Corporation


C-7 – Engineering hiPSC-derived 3D tissues using a comprehensive human transcription factor library
Alex Ng, CSO & Co-founder, GC Therapeutics


C-8 – Move over Matrigel®: fully defined synthetic matrices for human intestinal stem cell expansion and organogenesis
Victor Hernandez-Gordillo, Senior Postdoc Associate, MIT

3D Tissue and Disease Models


M-1 – A novel high-throughput multi-parametric drug screening method for 3D tumor spheroids using the Celigo image cytometer
Leo Chan, Technology R&D Manager, Nexelcom


M-2 – A spheroid tissue microarray platform for brain tumour drug development
Simon Plummer, Managing Director, MicroMatrices


M-3 – Ready to use 3D spheroid cultures as a standard tool to screen for drugs targeting cancer
Angel Garcia Martin, CEO, StemTek


M-4 – A racially/ethically diverse 3D PDX model of prostate cancer
Kristin Bircsak, Principal Scientist, Mimetas


M-5 – Characterizing drug response on 3D tumor spheroid invasion assay using a high-throughput optical coherence tomograph
Huang Yongyang, Graduate Student, Lehigh University


M-6In vitro models of human neuro-developmental disease using human pluripotent stem cells 
In-Hyun Park, Associate Professor, Yale University


M-7 – HypoSkin®, a standardized living human ex vivo skin model including adipose tissue as a toxicity model
following subcutaneous injection
Pascal Descargues, CEO, Genoskin, Inc.


M-8 – Using 3D human liver microtissues to model NASH progression in vitro for drug discovery and saftety testing
Radina Kostadinova, Product Manager, InSphero


M-9 – Assessment of DILI using 3D human liver microtissues
Judi Wardwell, Senior Application Scientist, InSphero


M-10 – Development of an in vitro 3D model system for testing PD-1/PDL-1 immune checkpoint inhibitors
Irina Agarkova, Senior Scientist, InSphero